PURPOSE: To investigate the influence of gravity and blink rate on lac
rimal drainage capacity and to learn whether lacrimal pump function ca
n be measured with the drop test. METHODS: The drop test: for lacrimal
drainage capacity was performed in 20 test subjects, aged 12 to 30 ye
ars. Drops of a known volume of lukewarm saline solution were repeated
ly instilled in the rear film for 3 minutes. Excessive saline solution
was then removed, and the volume drained by the lacrimal passages was
calculated. The drop test was performed both with the nasolacrimal du
ct. in a 45-degree position and with the nasolacrimal duct in a horizo
ntal position, The drop test was performed two times in each position,
with the individual reading and not reading, A lower blink rate was i
nduced by reading. RESULTS: There was a high correlation between blink
rate and lacrimal drainage when the nasolacrimal duct was in a horizo
ntal position. The volume drained with each blink was approximately 2
mu l. However, when gravity acted upon the fluid in the lacrimal sac-n
asolacrimal duct in the direction of the tear flow, the lacrimal drain
age capacity showed a significant but variable increase, and there was
no significant correlation between blink rate and lacrimal drainage c
apacity. CONCLUSIONS: Lacrimal drainage capacity in young individuals
was significantly affected by both blink rate and gravity. Lacrimal pu
mp function can be measured quantitatively with the drop test.