NON-AFRICAN BURKITT-LYMPHOMA PRESENTING WITH ORAL THRUSH AND AN ORBITAL MASS IN A CHILD

PURPOSE: To report an unusual case of orbital involvement with non-Afr ican Burkitt lymphoma in a child. METHODS: A 26-month-old boy develope d oral thrush and painless right proptosis with eyelid swelling. Magne tic resonance imaging disclosed a diffuse mass involving the inferior, lateral, and superior right orbit and both maxillary sinuses. Incisio nal biopsy of the orbital mass was performed. RESULTS: Histopathology disclosed diffuse infiltration of the orbital tissues by a high-grade lymphoid neoplasm that showed positive immunoreactivity for B-cell mar kers, Immunoglobulin gene rearrangement studies disclosed a characteri stic t(8;14) translocation consistent with a small, noncleaved maligna nt lymphoma of the Burkitt type. CONCLUSION: Non African Burkitt lymph oma may manifest with orbital involvement.