DIRECT N-3 ALKYLATION OF URACIL AND DERIVATIVES VIA N-1-[2-(TRIMETHYLSILYL)ETHOXYMETHYL] PROTECTION

Authors
ARIAS L GUZMAN A JAIMEFIGUEROA S LOPEZ FJ MORGANS DJ PADILLA F PEREZMEDRANO A QUINTERO C ROMERO M SANDOVAL L
Citation
L. Arias et al., DIRECT N-3 ALKYLATION OF URACIL AND DERIVATIVES VIA N-1-[2-(TRIMETHYLSILYL)ETHOXYMETHYL] PROTECTION, Synlett, (11), 1997, pp. 1233
Citations number
19
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
11
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):11<1233:DNAOUA>2.0.ZU;2-L
Abstract
Protection at N-1 position of uracil and uracil analogs as 2-(trimethy lsilyl)ethoxymethyl derivatives permits the clean alkylation at N-3. T hese protected uracils are quite stable in a wide range of pH.