ASYMMETRIC HYDROGENATION OF ALPHA-AMINOKETONE, BETA-AMINOKETONE, AND GAMMA-AMINOKETONE CATALYZED BY CATIONIC RHODIUM(I)(AMPP) COMPLEXES

Authors
DEVOCELLE M AGBOSSOU F MORTREUX A
Citation
M. Devocelle et al., ASYMMETRIC HYDROGENATION OF ALPHA-AMINOKETONE, BETA-AMINOKETONE, AND GAMMA-AMINOKETONE CATALYZED BY CATIONIC RHODIUM(I)(AMPP) COMPLEXES, Synlett, (11), 1997, pp. 1306
Citations number
19
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
11
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):11<1306:AHOABA>2.0.ZU;2-K
Abstract
The chiral cationic rhodium aminophosphine-phosphinite complexes 4-6 w ere applied successfully in the asymmetric hydrogenation of alpha- (7- 9), beta- (10, 11) and gamma- (12) aminoketone hydrochloride derivativ es leading to the corresponding aminoalcohols in up to 97, 93, and 92 % enantiomeric excesses for the three types of substrates respectively .