The accurate pre-operative evaluation of the intramedullary extent of
osteosarcoma is essential, as it determines the level of bone resectio
n, Radiographs, isotope: bent: and MR imaging scans have been consider
ed as reliable in detecting skeletal metastasis and skip lesions. We r
eport a case of osteosarcoma of the distal femur with a large skip les
ion proximally which was not visualized by either routine radiography
or bone scintigraphy, and was not included within the scan field on th
e: initial MR imaging scan. The implications on patient management and
possible reasons for failure of imaging to reveal the skip metastasis
are discussed.