APPLICATION OF THE DE DONDER RELATION TO THE MECHANISM OF CATALYTIC REACTIONS

The principle of microscopic reversibility at equilibrium is often inv oked in the context of the feasibility of postulated kinetic mechanism s. In this context, it is argued that the De Donder relation A upsilon greater than or equal to 0, relating the affinity A and the net rate upsilon of a chemical reaction, appears to be particularly incisive, a s it clearly applies to nonequilibrium systems, at the steady state or the quasi-steady state. In particular, when reactions or elementary s teps are involved in closed cycles, application of the De Donder relat ion leads to informative restrictions concerning postulated mechanisms .