HOW GRAPEFRUIT JUICE POTENTIATES DRUG BIOAVAILABILITY

Authors
FELDMAN EB
Citation
Eb. Feldman, HOW GRAPEFRUIT JUICE POTENTIATES DRUG BIOAVAILABILITY, Nutrition reviews, 55(11), 1997, pp. 398-400
Citations number
7
Journal title
Nutrition reviews → ACNP
ISSN journal
00296643
Volume
55
Issue
11
Year of publication
1997
Part
1
Pages
398 - 400
Database
ISI
SICI code
0029-6643(1997)55:11<398:HGJPDB>2.0.ZU;2-X
Abstract
Grapefruit juice enhances the effect of some commonly used medications by increasing their bioavailability via the selective down-regulation of a specific subfamily of the cytochrome P450 enzyme system in the s mall intestine.