NONALCOHOLIC STEATOHEPATITIS MASQUERADING AS AUTOIMMUNE HEPATITIS

Nonalcoholic steatohepatitis is an increasingly recognized clinicopath ologic condition. We report two cases of nonalcoholic steatohepatitis in middle-aged Japanese women whose clinical and laboratory data mimic ked autoimmune hepatitis. Histologic findings of both cases were defin ite steatohepatitis with portal and pericellular fibrosis. Both patien ts' HLA-DR haplotypes were DR4 and DR2, which are frequently observed in Japanese patients with autoimmune hepatitis. Our cases suggest a di versity in the pathogenesis of nonalcoholic steatohepatitis.