PATHWAY OF CHYMOTRYPSIN EVOLUTION SUGGESTED BY THE STRUCTURE OF THE FMN-BINDING PROTEIN FROM DESULFOVIBRIO-VULGARIS (MIYAZAKI-F)

Authors
LIEPINSH E KITAMURA M MURAKAMI T NAKAYA T OTTING G
Citation
E. Liepinsh et al., PATHWAY OF CHYMOTRYPSIN EVOLUTION SUGGESTED BY THE STRUCTURE OF THE FMN-BINDING PROTEIN FROM DESULFOVIBRIO-VULGARIS (MIYAZAKI-F), Nature structural biology, 4(12), 1997, pp. 975-979
Citations number
33
Journal title
Nature structural biology → ACNP
ISSN journal
10728368
Volume
4
Issue
12
Year of publication
1997
Pages
975 - 979
Database
ISI
SICI code
1072-8368(1997)4:12<975:POCESB>2.0.ZU;2-7
Abstract
The flavin mononucleotide (FMN)-binding protein from Desulfovibrio vul garis (Miyazaki F) is structurally related to a so far hypothetical si ngle-domain precursor of chymotrypsin, with the FMN-binding site coinc iding with part of the active site of the protease.