A PASSIVE TRANSMEMBRANE HELIX

Authors
ZHOU YF WEN J BOWIE JU
Citation
Yf. Zhou et al., A PASSIVE TRANSMEMBRANE HELIX, Nature structural biology, 4(12), 1997, pp. 986-990
Citations number
39
Journal title
Nature structural biology → ACNP
ISSN journal
10728368
Volume
4
Issue
12
Year of publication
1997
Pages
986 - 990
Database
ISI
SICI code
1072-8368(1997)4:12<986:>2.0.ZU;2-U
Abstract
Every residue of a putative transmembrane helix in diacylglycerol kina se can be converted to both alanine and leucine while maintaining high specific activity, indicating that some transmembrane helices play a relatively passive role in structure and function.