TREATMENT OF METHANOL POISONING WITH INTRAVENOUS 4-METHYLPYRAZOLE

Citation
Mj. Burns et al., TREATMENT OF METHANOL POISONING WITH INTRAVENOUS 4-METHYLPYRAZOLE, Annals of emergency medicine, 30(6), 1997, pp. 829-832
Citations number
18
Categorie Soggetti
Emergency Medicine & Critical Care
ISSN journal
01960644
Volume
30
Issue
6
Year of publication
1997
Pages
829 - 832
Database
ISI
SICI code
0196-0644(1997)30:6<829:TOMPWI>2.0.ZU;2-3
Abstract
Treatment of human methanol poisoning with the alcohol dehydrogenase i nhibitor, 4-methylpyrazole (fomepizole), has not been previously descr ibed. We report the clinical and toxicokinetic data of a patient with methanol poisoning who was treated with fomepizole. Formic acid levels remained undetectable during fomepizole treatment, the toxic effects of methanol were prevented, and the patient made a full recovery.