AROYLATION OF FUSED PYRIMIDINES - SYNTHESIS OF 4-AROYLFURO[2,3-D]PYRIMIDINES, 4-AROYLTHIENO[2,3-D]PYRIMIDINES, AND 4-AROYLISOXAZOLO[5,4-D]PYRIMIDINES

4-Aroylfuro[2,3-d]-(4), 4-aroylthieno[2,3-d]-(7 and 8), and 4-aroyliso xazolo[5,4-d]pyrimidines (13) were synthesized by aroylation of the fu sed chloro-(3a and 12) or bromopyrimidines (3b, 5, and 6) with areneca rbaldehydes (2) catalyzed by an imidazolium salt (1a). The fused aroyl pyrimidines (4 and 7) were also synthesized by oxidative decyanation o f alpha-phenylheteroareneacetonitriles (10 and 11).