On the U.S. west coast, the main toxin-producing algal species are din
oflagellates in the genus Alexandrium that cause paralytic shellfish p
oisoning (PSP) and diatoms in the genus Pseudo-nitzschia that produce
domoic acid and cause domoic acid poisoning (DAP). Other harmful speci
es, including the raphidophyte Heterosigma nkashiwo and the diatoms Ch
aetoceros convolutus and Chaetoceros concavicornis, kill fish at aquac
ulture sites, but are not harmful to humans. Water discolorations (red
tides) caused by nontoxic dinoflagellates also occur throughout the a
rea. Early records, partially based on local native lore, suggest that
algal toxins have been present along this coast for hundreds of years
, but actual scientific information is sparse. We review what is now k
nown about harmful algal blooms in this vast area, including the hydro
graphic regimes that induce and(or) support blooms, bloom dynamics, an
d the biology of the causative species.