AGE AND SEX EFFECTS ON BRAIN MORPHOLOGY

Authors
PASSE TJ RAJAGOPALAN P TUPLER LA BYRUM CE MACFALL JR KRISHNAN KRR
Citation
Tj. Passe et al., AGE AND SEX EFFECTS ON BRAIN MORPHOLOGY, Progress in neuro-psychopharmacology & biological psychiatry, 21(8), 1997, pp. 1231-1237
Citations number
17
Categorie Soggetti
Neurosciences,"Clinical Neurology","Pharmacology & Pharmacy",Psychiatry
Journal title
Progress in neuro-psychopharmacology & biological psychiatry → ACNP
ISSN journal
02785846
Volume
21
Issue
8
Year of publication
1997
Pages
1231 - 1237
Database
ISI
SICI code
0278-5846(1997)21:8<1231:AASEOB>2.0.ZU;2-K
Abstract
1. Brain morphology can be assessed readily in vivo using magnetic res onance imaging (MRI). 2. In this study, the effects of age and sex on whole-brain morphology were examined using an operator-controlled comp uter-segmentation protocol. 3. Results indicated that age was associat ed with gray-matter volume reduction. 4. Brain-size differences betwee n males and females were primarily attributable to white-matter volume . 5. This study confirms the importance of controlling for age and sex in brain-morphology studies.