DETECTION OF HPV-16 DNA BY PCR IN HISTOLOGICALLY CANCER-FREE LYMPH-NODES FROM PATIENTS WITH CERVICAL-CANCER

Authors
BAAY MFD KOUDSTAAL J HOLLEMA H DUK JM BURGER MPM QUINT WGV STOLZ E HERBRINK P
Citation
Mfd. Baay et al., DETECTION OF HPV-16 DNA BY PCR IN HISTOLOGICALLY CANCER-FREE LYMPH-NODES FROM PATIENTS WITH CERVICAL-CANCER, Journal of Clinical Pathology, 50(11), 1997, pp. 960-961
Citations number
11
Journal title
Journal of Clinical Pathology → ACNP
ISSN journal
00219746
Volume
50
Issue
11
Year of publication
1997
Pages
960 - 961
Database
ISI
SICI code
0021-9746(1997)50:11<960:DOHDBP>2.0.ZU;2-U
Abstract
The prognostic value of detection of human papillomavirus (HPV) type 1 6 DNA in histologically cancer free lymph nodes was assessed in left o bturator lymph nodes from cervical cancer patients with HPV-16 positiv e primary tumours. HPV-16 DNA was detected by polymerase chain reactio n in 12 of 35 patients with histologically cancer free lymph nodes. Of these 12 patients, only one developed a recurrence, suggesting HPV-16 DNA detection in cancer free lymph nodes has no prognostic value.