SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME PENICILLIN AND CEPHALOSPORIN DERIVATIVES

Citation
Ai. Hashem et al., SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME PENICILLIN AND CEPHALOSPORIN DERIVATIVES, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(2), 1997, pp. 196-198
Citations number
5
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
03764699
Volume
36
Issue
2
Year of publication
1997
Pages
196 - 198
Database
ISI
SICI code
0376-4699(1997)36:2<196:SAAAOS>2.0.ZU;2-W
Abstract
6-Aminopenicillanic acid and 7-aminodeacetoxycephalosporanic acid reac t with 4-acetylaminobenzene sulphonyl chloride, phenylacetic acid-4-su lphonyl chloride and uracil-5-sulphonyl chloride to give new penicilli n and cephalosporin derivatives bearing sulphonamide groups. The resul ting antibiotics have been tested for their antimicrobial activities.