EFFICACY OF ANTITHROMBIN CONCENTRATES IN TREATMENT FOR ASTHMATIC SYMPTOMS COMPLICATED IN ANTITHROMBIN ABNORMALITY WITH NO HEPARIN-BINDING ACTIVITY

Authors
YOSHIDA Y NIIYA K MARUYAMA M OOSAKI R FUJISHITA T KOBAYASHI M SAKURAGAWA N
Citation
Y. Yoshida et al., EFFICACY OF ANTITHROMBIN CONCENTRATES IN TREATMENT FOR ASTHMATIC SYMPTOMS COMPLICATED IN ANTITHROMBIN ABNORMALITY WITH NO HEPARIN-BINDING ACTIVITY, Clinical and applied thrombosis/hemostasis, 3(4), 1997, pp. 288-289
Citations number
9
Journal title
Clinical and applied thrombosis/hemostasis → ACNP
ISSN journal
10760296
Volume
3
Issue
4
Year of publication
1997
Pages
288 - 289
Database
ISI
SICI code
1076-0296(1997)3:4<288:EOACIT>2.0.ZU;2-D
Abstract
It is well-known that pulmonary embolism sometimes accompanies a bronc hoconstrictive symptom, but the precise mechanism is not clearly under stood. We report a unique case of antithrombin (AT) abnormality with n o heparin-binding activity accompanied by pulmonary thromboembolism an d asthmatic symptoms. Keeping AT activity >60% by infusion of AT conce ntrates, we successfully treated the asthmatic symptom, which did not respond to ordinary treatment for bronchial asthma and the anticoagula nt therapy by warfarin potassium for pulmonary thromboembolism.