Ba. Lafaut et al., FUNDUS FLUORESCEIN ANGIOGRAPHY OF PATIENTS WITH SEVERE HYPERTENSIVE NEPHROPATHY, Graefe's archive for clinical and experimental ophthalmology, 235(12), 1997, pp. 749-754
Purpose: To analyze the fluorescein angiograms of patients with hypert
ensive renal failure. Methods: Fluorescein angiograms were obtained of
34 patients with hypertensive renal failure. The glomerular filtratio
n was less than 20 ml/min in each patient. Results: Capillary nonperfu
sion and a coarse retinal capillary bed are the hallmark of the hypert
ensive retinopathy. Tortuous retinal arterioles or tortuous retinal ar
teriovenous anastomoses are observed. It is suggested that capillary c
ollaterals shunt arteriolar obstructions or short-cut nonperfused capi
llary beds; these remodel into tortuous arterioles or arteriovenous an
astomoses with regular caliber. Elschnig spots and delayed choroidal f
illing are signs of hypertensive choroidopathy. Depigmentation spots o
f the retinal pigment epithelium without a central pigment clump are c
onsidered atypical Elschnig spots. Conclusions: Retinal pigment epithe
lial changes are permanent scars of hypertensive choroidopathy, while
coarse retinal capillary bed and tortuous retinal arterioles or arteri
ovenous anastomoses are the result of hypertensive retinopathy in thes
e patients with hypertensive renal failure.