VOLUNTARY ALCOHOL-DRINKING SELECTIVELY ACCELERATES DOPAMINE RELEASE IN THE VENTRAL STRIATUM AS REFLECTED BY 3-METHOXYTYRAMINE LEVELS

Authors
HONKANEN A AHTEE L KORPI ER
Citation
A. Honkanen et al., VOLUNTARY ALCOHOL-DRINKING SELECTIVELY ACCELERATES DOPAMINE RELEASE IN THE VENTRAL STRIATUM AS REFLECTED BY 3-METHOXYTYRAMINE LEVELS, Brain research, 774(1-2), 1997, pp. 207-210
Citations number
18
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
774
Issue
1-2
Year of publication
1997
Pages
207 - 210
Database
ISI
SICI code
0006-8993(1997)774:1-2<207:VASADR>2.0.ZU;2-4
Abstract
Alcohol-preferring Alko, Alcohol (AA) rats with free access to food an d water were taught to voluntarily consume 10% alcohol solution during 20-min sessions. After the drinking session, rats had elevated dopami ne release (as reflected by 3-methoxytyramine concentrations) in the n ucleus accumbens, olfactory tubercle, and caudate-putamen When alcohol solution was replaced by plain water, dopamine release was increased only in the caudate-putamen, indicating selective activation of the me solimbic dopaminergic pathway by alcohol. (C) 1997 Elsevier Science B. V.