INTERACTION OF SULFHYDRYL-REAGENTS WITH K+ TRANSPORT IN ADRENAL CHROMAFFIN GRANULES

Authors
SZEWCZYK A LOBANOV NA NOWOTNY M NALECZ MJ
Citation
A. Szewczyk et al., INTERACTION OF SULFHYDRYL-REAGENTS WITH K+ TRANSPORT IN ADRENAL CHROMAFFIN GRANULES, Acta Neurobiologiae Experimentalis, 57(4), 1997, pp. 329-332
Citations number
13
Journal title
Acta Neurobiologiae Experimentalis → ACNP
ISSN journal
00651400
Volume
57
Issue
4
Year of publication
1997
Pages
329 - 332
Database
ISI
SICI code
0065-1400(1997)57:4<329:IOSWKT>2.0.ZU;2-L
Abstract
In the present study the functional role of SH groups in the Ca2+-inde pendent K+-selective channel activity in the membrane of bovine adrena l gland chromaffin granules has been studied. Ionic channel activity h as been estimated using Rb-86(+), a K+ analogue, flux measurements. Th e inhibition of chromaffin granules K+ channel by SH modifying agents, such as N-ethylmaleimide, mersalyl and phenylarsenoxide, is described .