GLYCOPROTEINS GB, GD, AND GHGL OF HERPES-SIMPLEX VIRUS TYPE-1 ARE NECESSARY AND SUFFICIENT TO MEDIATE MEMBRANE-FUSION IN A COS CELL TRANSFECTION SYSTEM

Authors
TURNER A BRUUN B MINSON T BROWNE H
Citation
A. Turner et al., GLYCOPROTEINS GB, GD, AND GHGL OF HERPES-SIMPLEX VIRUS TYPE-1 ARE NECESSARY AND SUFFICIENT TO MEDIATE MEMBRANE-FUSION IN A COS CELL TRANSFECTION SYSTEM, Journal of virology, 72(1), 1998, pp. 873-875
Citations number
24
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
72
Issue
1
Year of publication
1998
Pages
873 - 875
Database
ISI
SICI code
0022-538X(1998)72:1<873:GGGAGO>2.0.ZU;2-0
Abstract
Herpes simplex virus type 1 glycoproteins gB, gD, and gHgL were expres sed by transient transfection of Cos cells. Polykaryocyte formation ab ove the background level seen in untransfected controls was observed o nly if all three components were expressed. Thus, gB, gD, and gHgL are necessary and sufficient to induce membrane fusion.