Gr. Buttermann et al., REVISION OF FAILED LUMBAR FUSIONS - A COMPARISON OF ANTERIOR AUTOGRAFT AND ALLOGRAFT, Spine (Philadelphia, Pa. 1976), 22(23), 1997, pp. 2748-2755
Study Design. The radiographic and clinical results of two different a
nterior structural grafts were compared in 38 patients who had combine
d anterior-posterior revision surgery for failed lumbar fusion. Object
ives. Failed lumbar fusion surgery, such as pseudarthrosis or flatback
deformity, may result in disabling pain. The optimum revision techniq
ue has yet to be defined. The authors of the current study sought to d
etermine which of two different types of anterior graft yields the bes
t results. Summary of Background Data. Posterior procedures for revisi
on of a failed lumbar fusion have not yielded reliably successful resu
lts. A combined anterior-posterior approach may be effective in restor
ing sagittal balance and enhancing fusion rates. Recent studies have s
hown femoral ring allografts to be effective in lumbar fusion revision
, but no studies have compared these with other types of structural gr
afts. Methods. Thirty-eight patients with pseudarthrosis were treated
with combined anterior-posterior lumbar spine fusion using either femo
ral ring allografts (26 patients) or tricortical iliac autografts (12
patients). Radiographic follow-up examination and retrospective patien
t self-assessment questionnaires were used to evaluate outcomes. Resul
ts were assessed by independent reviewers after a mean follow-up perio
d of 35 months. Results. Radiographic follow-up examination revealed a
cceptably low pseudarthrosis rates for structural autografts (0%) and
allografts (6%). The questionnaires revealed significant improvement i
n pain for both groups. Allograft patients showed greater improvement
in function, less pain medication usage, and higher overall success ra
tes (83%) than autograft patients (64%). Conclusions. Femoral ring all
ografts are as effective, clinically and radiographically, as tricorti
cal iliac autografts when used as an anterior structural element in re
vision lumbar spine fusion in patients who have undergone multiple sur
gical procedures for pseudarthrosis or flatback deformity. The slightl
y greater improvement for the allograft group needs to be confirmed in
a larger study.