OBJECTIVE: To determine if there is a difference in the crown-rump len
gth (CRL) between male and female fetuses in the first trimester. STUD
Y DESIGN: CRL was determined in 77 normal twin pairs at the time of ch
orionic villus sampling. The sex of each fetus was assigned based upon
the results of the sampling. RESULTS: A small difference was found be
tween the CRL of males as compared to females, but this teas not stati
stically significant. However, if there was a difference in size betwe
en the twin pairs, the odds were 1.5:1 that the larger would be male.
CONCLUSION: There is no clinically significant difference in size betw
een male and female fetuses in the first trimester of pregnancy.