A 16-year-old girl with 3 clinical episodes of mononucleosis during a
period of more than 2 year is presented, The patient had persistently
elevated VCA-IgM antibodies during follow-up for 15 months until she b
ecame EBNA-positive, This is a case of prolonged primary EBV infection
and late seroconversion as clinical restitution and development of EB
NA antibodies occurred 2 year after the onset of clinical illness.