BACKGROUND: This is a retrospective review from March 1994 through Oct
ober 1996 of 78 patients who underwent laparoscopic Nissen fundoplicat
ion for gastroesophageal reflux disease (GERD). The purpose of this st
udy was to evaluate the postoperative results and complications. METHO
DS: The patient profile included 38 men and 40 women with a mean age o
f 46 years (range 11 to 81). The main preoperative symptoms included h
eartburn (92%), respiratory problems (42%), and dysphagia (32%). Preop
erative assessment included esophagogastroduodenoscopy, upper gastroin
testinal series, esophageal manometry, and 24-hour pH monitoring. Esse
ntial indications for surgery included esophagitis (83%), Barrett's es
ophagus without dysplasia (22%), and esophageal stricture (23%). All p
atients underwent a 360-degree wrap with a Maloney dilator and divisio
n of the short gastric vessels. RESULTS: The mean operative time was 2
06 minutes (range 90 to 455). The average time for patients to tolerat
e a full liquid diet was 1.2 days, and the mean hospital stay was 2.4
days. Current follow-up, from 3 to 36 months, showed complete resoluti
on of heartburn without medications in 67 patients (86%), occasional h
eartburn in 8 patients (10%), and slight improvement of heartburn in 3
patients (4%). Five patients with preoperative Barrett's metaplasia s
howed no evidence of it postoperatively (n = 2) or marked regression (
n = 3). CONCLUSION: Laparoscopic Nissen fundoplication is the procedur
e of choice for patients with complicated GERD. (C) 1997 by Excerpta M
edica, Inc.