BACKGROUND: A 10% to 20% negative appendectomy rate has been accepted
in order to minimize the incidence of perforated appendicitis with its
increased morbidity. We reviewed our experience with appendicitis in
order to determine the incidence of negative appendectomies and perfor
ation, and the role of delay in diagnosis or treatment. METHODS: We re
viewed 659 appendectomies performed over a 12-month period. incidental
and pediatric appendectomies were excluded. RESULTS: Seventy-five per
cent of patients were male and 25% female. Nine percent had negative a
ppendectomies and 28% had perforated appendicitis. Perforated appendic
itis resulted in increased morbidity and length of stay. Delay in pres
entation greater than 12 hours after the onset of symptoms significant
ly increased the perforation rate. In-hospital delay did not affect pe
rforation rate.CONCLUSIONS: We have achieved a negative appendectomy r
ate lower than that in other reported series, while maintaining-an acc
eptable perforation rate. In the majority of patients, perforated appe
ndicitis is a result of late presentation. (C) 1997 by Excerpta Medica
, Inc.