Osteoporosis, one of the most prevalent diseases associated with aging
, is characterized by a low bone mass and microarchitectural deteriora
tion of bone tissue leading to increased susceptibility of fracture. T
he management of osteoporotic patients relies especially on the static
measurement of bone mass as bone mineral and dynamic changes of bone
turn over. New developments of bone mineral density measurement techni
ques and biochemical markers of bone turnover are reviewed. Their clin
ical uses for the management of patients with osteoporosis are discuss
ed.