A patient with papilloedema due to idiopathic intracranial hypertensio
n developed bilateral progressive peripapillary myelination, This acqu
ired myelination suggests a breakdown of the normal barrier to oligode
ndrocyte migration into the retina. However, ultrastructural studies o
f developmental and acquired myelination in animals have consistently
found that the myelin is formed by peripheral nervous system myelin fo
rming cells (Schwann cells) rather than central nervous system oligode
ndrocytes.