SIAMYL GLYOXYLATE AS AN EFFICIENT ENOPHILE IN THE LEWIS-ACID MEDIATEDGLYOXYLATE ENE-REACTION WITH ALLYLIC ETHERS - APPLICATION TO THE SYNTHESIS OF A TAXOL A-RING SUBUNIT

Authors
WENNERBERG J POLLA M FREJD T
Citation
J. Wennerberg et al., SIAMYL GLYOXYLATE AS AN EFFICIENT ENOPHILE IN THE LEWIS-ACID MEDIATEDGLYOXYLATE ENE-REACTION WITH ALLYLIC ETHERS - APPLICATION TO THE SYNTHESIS OF A TAXOL A-RING SUBUNIT, Journal of organic chemistry, 62(25), 1997, pp. 8735-8740
Citations number
33
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
62
Issue
25
Year of publication
1997
Pages
8735 - 8740
Database
ISI
SICI code
0022-3263(1997)62:25<8735:SGAAEE>2.0.ZU;2-7
Abstract
In contrast to other simple alkyl glyoxylates, siamyl glyoxylate (la) proved to be an effective enophile in the glyoxylate ene-reaction with the allylic ether 2a, which we earlier used for the synthesis of the A-ring subunit of taxol.