INNOVATIVE APPROACHES TO NOVEL ANTIBACTERIAL DRUG DISCOVERY

Increasing antibiotic resistance in microorganisms and new emerging pa thogens have become a major problem in our society. Rising to satisfy this urgent medical need is a recent confluence of powerful new drug d iscovery technologies: combinatorial chemistry; sequence and functiona l genomic analysis; and novel methods of high-throughput screening. Th e combination of these technologies will bring to bear untapped power in the search for new antimicrobials. (C) Current Biology Ltd ISSN 095 8-1669.