DOES HYDROSALPINX REDUCE THE PREGNANCY RATE AFTER IN-VITRO FERTILIZATION

Objective: To determine the effect of hydrosalpinges on the pregnancy rate in an IVF program. Design: Multicentric retrospective analysis of clinical and laboratory data. Setting: Two assisted reproductive tech nology centers in university hospitals.Patient(s): Four hundred forty- three women, under 38 years of age, with pure tubal infertility. The p atients mere classified into the following five groups: bilateral hydr osalpinges (n = 37), unilateral hydrosalpinx (it = 54), bilateral tuba l occlusion(n = 207), unilateral tubal occlusion (n = 55), and severe tubal disease without complete occlusion (n = 90). Main Outcome Measur e(s): Pregnancy and implantation rates. Result(s): The pregnancy and t he implantation rates per transfer (12.3% and 5.4%) obtained by vr ome n with bilateral hydrosalpinges are significantly lower than the rates (means = 23.1% and 12%) for all other tubal infertility groups.Conclu sion(s): Bilateral hydrosalpinges have a deleterious effect on the out come of IVF program. (C) 1997 by American Society for Reproductive Med icine.