FOLLICLE ASPIRATION, SPERM INJECTION, AND ASSISTED RUPTURE (FASIAR) -A SIMPLE NEW ASSISTED REPRODUCTIVE TECHNIQUE

Objective: To describe the first successful application of a new ferti lity-enhancing technique. Design: Case report. Setting: Academic ferti lity program. Patient(s): A 36-year-old nulligravid woman undergoing i nseminations with frozen-thawed donor sperm. Intervention(s): Ovarian superovulation, follicle aspiration, sperm injection, and assisted fol licular rupture. Main Outcome Measure(s): Assessment of feasibility of technique and pregnancy outcome. Result(s): After failing to conceive during 16 cycles of IUI, the patient successfully achieved an ongoing pregnancy during the second follicle aspiration, sperm injection, and assisted rupture (FASIAR) attempt. Conclusion(s): Follicle aspiration , sperm injection, and assisted rupture combines the concepts of super ovulation, IUI, and peritoneal oocyte and sperm transfer to obviate th e possibility of luteinized unruptured follicle syndrome, assist. oocy te release, and ensure gamete intermixing. It also can be used to redu ce the number of ovulating oocytes and thus to reduce the risk of mult iple gestations. Follicle aspiration, sperm injection, and assisted ru pture is a new, simple, office-based procedure that does not require e mbryologic expertise beyond sperm preparation as for IUI, yet promises to be more successful than IUI. (C) 1997 by American Society for Repr oductive Medicine.