LIMITING DILUTION ANALYSIS OF PRIMARY CYTOTOXIC T-CELL PRECURSORS

Authors
ZAUDERER M SINGER A
Citation
M. Zauderer et A. Singer, LIMITING DILUTION ANALYSIS OF PRIMARY CYTOTOXIC T-CELL PRECURSORS, Journal of immunological methods, 208(1), 1997, pp. 85-90
Citations number
7
Journal title
Journal of immunological methods → ACNP
ISSN journal
00221759
Volume
208
Issue
1
Year of publication
1997
Pages
85 - 90
Database
ISI
SICI code
0022-1759(1997)208:1<85:LDAOPC>2.0.ZU;2-T
Abstract
An efficient colorimetric assay has been adapted for limiting dilution analysis of cytotoxic T-cell precursors. Application of this assay in a suitable experimental model of thymic education could be especially useful in identifying factors that shape the CD8 T-cell repertoire. T he essential elements of such a model are described here and elsewhere . (C) 1997 Elsevier Science B.V.