HEDGEHOG SIGNALING - CI COMPLEX CUTS AND CLASPS

Authors
Citation
D. Kalderon, HEDGEHOG SIGNALING - CI COMPLEX CUTS AND CLASPS, Current biology, 7(12), 1997, pp. 759-762
Citations number
12
Journal title
ISSN journal
09609822
Volume
7
Issue
12
Year of publication
1997
Pages
759 - 762
Database
ISI
SICI code
0960-9822(1997)7:12<759:HS-CCC>2.0.ZU;2-L
Abstract
Hedgehog (Hh) signalling in Drosophila inhibits partial proteolysis of the transcription factor Cubitus interruptus (Ci), and the ability of a complex containing Ci and the kinesin-related protein Costal-2 to b ind microtubules. These changes are proposed to turn Ci from a repress or to an activator of Hh-target genes.