G. Dreyfus et al., LEFT-VENTRICULAR REDUCTION (BATISTA) - A NEW SURGICAL OPTION IN DILATED CARDIOMYOPATHY, Archives des maladies du coeur et des vaisseaux, 90(11), 1997, pp. 1521-1525
Cardiac transplantation remains the standard treatment for severe card
iomyopathy resistant to medical therapy. However, new techniques may h
elp to put this off. Two patients with dilated cardiomyopathy were tre
ated surgically since October 1996, one aged 48 and the other 52. They
were in NYHA Class IV and one was dependant on inotropic drugs. Both
had relative or absolute contra-indications to tranplantation. The lef
t ventricular end diastolic dimensions were over 70 mm with mild mitra
l regurgitation and fractional shortening of less than 12 %. Coronary
angiography was normal. They were operated in October 1996 and January
1997. The procedure consisted of correction of mitral regurgitation (
annuloplasty) and of reduction of left ventricular volume by a triangu
lar resection from the apese to the base of the heart. At histological
examination, the resected myocardium measured 11 to 13 cm long and 5
to 7 cm at its base. The two patients were discharged from hospital af
ter 45 and 30 days. There were no clinical signs of cardiac failure. F
ollow-up investigations showed a marked decrease in ventricular volume
s, the end diastolic dimensions changing from 70 to 52 mm in the first
, and from 76 to 54 mm in the second patient. The corresponding values
of fractional shortening increased from 11 to 20 % and from 6 to 17 %
. Left ventricular volumes decreased from 328 mL (end diastole) and 25
9 mL (end systole) to 140 mL and 74 mL in the first case, and from 300
mL (end diastole) and 280 mL (end systole) to 122 mL and 83 mL respec
tively in the second case. The ejection fraction increased from 20 to
40 % and from 10 to 32 %. These preliminary results show that the theo
retical advantages of this surgical technique correspond to a practica
l reality. Larger series of patients are required to determine the opt
imal indications.