Nu. Zitzmann et al., RESORBABLE VERSUS NONRESORBABLE MEMBRANES IN COMBINATION WITH BIO-OSSFOR GUIDED BONE REGENERATION, The International journal of oral and maxillofacial implants, 12(6), 1997, pp. 844-852
The purpose of this clinical investigation was to compare the new reso
rbable collagen membrane, Bio-Gide, to the conventional expanded polyt
etrafluoroethylene material (Gore-Tex) for guided bone regeneration in
situations involving exposed implant surfaces. Over a 2-year period,
25 split-mouth patients were treated randomly: one defect site was tre
ated with Bio-Gide and the other defect site with Gore-Tex; all 84 def
ects were filled with Bio-Oss and covered with the respective membrane
, The defect types, their dimensions, and their morphology were measur
ed in detail initially and at re-entry to allow for calculation of the
exposed implant surface. Changes in defect surface for both types of
membranes were statistically significant (P < .0001); however; no stat
istical significance (P > .94) could be detected between the two membr
anes. The mean average percentage of bone fill was 92% for Bio-Gide an
d 78% for Gore-Tex sites. In the latter group, 44% wound dehiscences a
nd/or premature membrane removal occurred. The resorbable membrane, Bi
o-Gide, in combination with a bone graft, can be a useful alternative
to the well-established expanded polytetrafluoroethylene membranes.