INFRARED AND RAMAN-SPECTRA OF ALKYLATED GUANINE DERIVATIVES

The infrared and Raman spectra of 9-methylguanine, 9-ethylguanine and 1,9-dimethylguanine in the solid state are reported and discussed. Hyd rogen bonds in the solid guanine derivatives bring about strong pertur bations in the spectra from those of the isolated molecules, The resul ts are discussed in terms of structural data from X-ray diffraction st udies, The infrared spectra of guanine derivatives are compared with t he spectra of these molecules isolated in low temperature argon matric es, This comparison allows the determination of the frequency changes due to hydrogen bonding and the interpretation of their vibrational sp ectra in terms of the normal modes calculated for the isolated guanine molecule. (C) 1997 Elsevier Science B.V.