TREATMENT OF CONVULSIVE STATUS EPILEPTICUS WITH PROPOFOL - CASE-REPORT

Citation
Am. Harrison et al., TREATMENT OF CONVULSIVE STATUS EPILEPTICUS WITH PROPOFOL - CASE-REPORT, Pediatric emergency care, 13(6), 1997, pp. 420-422
Citations number
21
Categorie Soggetti
Pediatrics,"Emergency Medicine & Critical Care
Journal title
ISSN journal
07495161
Volume
13
Issue
6
Year of publication
1997
Pages
420 - 422
Database
ISI
SICI code
0749-5161(1997)13:6<420:TOCSEW>2.0.ZU;2-Z
Abstract
Introduction: Convulsive status epilepticus (CSE) refractory to treatm ent with benzodiazepines, phenobarbital, and phenytoin presents a chal lenge to pediatric emergency and critical care specialists. Prompt sei zure control mag prevent mortality and morbidity. Case: A nine-month-o ld girl with hereditary fructose intolerance had prolonged, refractory CSE. Her seizures promptly stopped after administration of propofol ( 3 mg/kg bolus followed by infusion of 100 mu g/kg/min). This dose resu lted in electroencephalographic burst suppression, She required endotr acheal intubation, invasive hemodynamic monitoring, and pressor suppor t. Discussion: This is the first pediatric case of prolonged, refracto ry CSE treated wilt propofol. The adult experience is reviewed. Propof ol should be used only in a setting where definitive airway control an d hemodynamic support if possible.