METALLOTHIONEINS AND CADMIUM UPTAKE BY THE LIVER IN BUFO-ARENARUM

Authors
PEREZCOLL CS HERKOVITS J FRIDMAN O DANIEL P DERAMO JL
Citation
Cs. Perezcoll et al., METALLOTHIONEINS AND CADMIUM UPTAKE BY THE LIVER IN BUFO-ARENARUM, Environmental pollution, 97(3), 1997, pp. 311-315
Citations number
18
Categorie Soggetti
Environmental Sciences
Journal title
Environmental pollution → ACNP
ISSN journal
02697491
Volume
97
Issue
3
Year of publication
1997
Pages
311 - 315
Database
ISI
SICI code
0269-7491(1997)97:3<311:MACUBT>2.0.ZU;2-Q
Abstract
Bufo arenarum females were treated daily with 0.5 mg Cd kg(-1) during 10 days to evaluate the uptake of this heavy metal and the induction o f metallothionein synthesis in the liver. The liver incorporated 26% o f the Cd administered, about 6.5 times higher than the average uptake of the other tissues of B. arenarum. Three protein fractions from the B. arenarum liver bound Cd, and were induced by this xenobiotic up to approx. 24 times above the basal level of these proteins. (C) 1997 Els evier Science Ltd.