Many countries now have registers of assisted conception that were ini
tially set up to evaluate the effectiveness of treatment, to monitor p
regnancy outcomes and the health of treated women, and to assess any i
mmediate risks for the women and their children, World reports, based
on information from national registers, have enabled international com
parisons of the extent to which the various techniques of assisted con
ception are used to treat infertile couples, as well as comparisons of
pregnancy outcome, The reports also provide comparative data on pregn
ancy rates in populations rather than in single in-vitro fertilization
(IVF) centres, To determine whether newly introduced techniques such
as intracytoplasmic sperm injection are associated with any increased
risks of birth defects or other adverse outcomes, information notified
to registers will often need to be supplemented by clinical reports o
r by linkage of data in IVF registers and other health data systems, F
urther efforts to improve the quality of information on assisted conce
ption within each country and internationally need to be well supporte
d so that the effectiveness of treatment and the outcomes of treated c
ouples and their children can be evaluated properly.