Background-Regular cyclists have been found to have a lower incidence
of coronary events (CHD) than the general public. Non-invasive studies
have found that competitive cyclists develop a cardiac hypertrophy th
at is physiological and reversible. Methods-To obtain pathological sup
port for these observations, the postmortem findings of 32 cyclists ki
lled in accidents have been compared with those in a control group of
32 other road traffic accidents, which were matched with the cyclists
by sex, age, and year of death. Findings-Large myocardial scars and co
mplete blockage of a coronary artery were only found in the controls;
serious stenoses of coronary arteries (>50%) were found in eight contr
ols but in only one of the cyclists. Of the cyclists, 25 had normal co
ronary arteries as compared with 14 of the controls. The mean age of t
he cyclists with evidence of CHD was greater than that of similarly af
fected controls. The heart weights of the two groups were almost the s
ame but heart weight varied with the degree of CHD. The heart weight o
f the healthy cyclists (389 g) was greater than that of the healthy co
ntrols (371 g) but this was not statistically significant. Interpretat
ion-The results are in keeping with the concept that regular exercise
provides some protection from the development of CHD and that cycling
may be a valuable form of exercise in this respect. This may be of imp
ortance as the number of physically active occupations declines.