M. Deonis et al., THE DEVELOPMENT OF MUAC-FOR-AGE REFERENCE DATA RECOMMENDED BY A WHO EXPERT COMMITTEE, Bulletin of the World Health Organization, 75(1), 1997, pp. 11-18
Low mid-upper-arm circumference (MUAC), determined on the basis of a f
ixed cut-off value, has commonly been used as a proxy for low weight-f
or-height (wasting). The use of a fixed cut-off value was based on the
observation that MUAC showed small age- and sex-specific differences.
However, in 1993, a WHO Expert Committee concluded that age independe
nce is not reflected in the true pattern of mid-upper arm growth, reco
mmended the use of MUAC-for-age, and presented age- and sex-specific M
UAC reference data developed with observations obtained from a represe
ntative sample of children in the USA aged 6-59 months. In this articl
e, we explain the methodology for the development of these data, prese
nt age- and sex-specific growth curves and tables and discuss the appl
ications and limitations of MUAC as a nutritional indicator. To develo
p the reference data, estimates were first obtained for the mean and s
tandard deviation of MUAC for each month of age using 7-month segmenta
l regression equations, a 5th-degree and a 3rd-degree polynomial in ag
e was then used to describe the mean and standard deviation, respectiv
ely, of MUAC-for age. These curves show important age-specific differe
nces, and significant sex-specific differences for boys and girls <24
months of age. Correct interpretation of MUAC with regard to nutrition
al status requires the use of MUAC-for-age reference data such as thos
e presented here.