Y. Akama et al., CHROMATOGRAPHIC BEHAVIOR OF THE CHROMIUM(III) COMPLEX OF 1-PHENYL-3-METHYL-4-BENZOYL-5-PYRAZOLONE, Journal of chromatography, 789(1-2), 1997, pp. 479-483
The separation of the two geometrical isomers of the chromium(III) com
plex of 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone was carried out using
acetonitrile-water (90:10, v/v) and n-hexane-tetrahydrofuran (70:30,
v/v) as the mobile phases for an ODS column and a silica gel column, r
espectively. Identification of the isomers was performed using a high-
performance liquid chromatography-continuous flow fast atom bombardmen
t-mass spectrometry system. It was found that the fac complex eluted f
irst, followed by the mer complex on the ODS column. (C) 1997 Elsevier
Science B.V.