Se. Robertson et al., CONTROL OF RUBELLA AND CONGENITAL-RUBELLA SYNDROME (CRS) IN DEVELOPING-COUNTRIES .2. VACCINATION AGAINST RUBELLA, Bulletin of the World Health Organization, 75(1), 1997, pp. 69-80
In 1995-96 we conducted a review of rubella immunization strategies. W
orldwide, 78 countries (more than one-third) reported a national polic
y of using rubella vaccine. This was closely related to country econom
ic status. Based on the United Nations country classification, rubella
vaccine is used in 92% of industrialized countries, 36% of those with
economies-in-transition, and 28% of developing countries. Cases of co
ngenital rubella syndrome (CRS) may be prevented as follows: by provid
ing direct protection to women and/or schoolgirls (a selective vaccina
tion strategy); by vaccinating boys and girls to provide indirect prot
ection by reducing the transmission of rubella virus (a childhood vacc
ination strategy); or by a combination of these approaches (a combined
strategy). A combined strategy was most commonly reported (60% of cou
ntries); seven countries (9%) reported a selective strategy; and 24 co
untries (31%) reported only childhood immunization. Experience has sho
wn that it is essential to include vaccination of women of childbearin
g age in any rubella control strategy. Childhood vaccination alone may
pose a risk of an increase in CRS cases. Although many countries have
introduced rubella vaccine, few report any data on the impact of vacc
ination. Countries using rubella vaccine need to establish surveillanc
e for rubella and CRS and monitor coverage in each of the target group
s.