The behaviour, under burn scars , of three different alloplastic mater
ials, silicone, Medpor and Proplast, was compared in an animal model.
A standard burn wound was created in rats, and 3 months later silicone
, medpor and proplast alloplasts were placed under the burn scar. The
rats were followed for another 3 months and ulceration and/or alloplas
t exposure rates were evaluated. At the end of this period specimens w
ere examined histologically for the thickness of the fibrous capsule a
round the implant, thickness of the overlying tissue, tissue ingrowth
and vascularization of the implants. Ulceration and exposure occurred
in 2 of the 12 Medpor, 2 of the 12 Proplast and none of the 12 silicon
e implants. Fibrous capsule was significantly thicker around the silic
one implants. Tissue ingrowth and vascularization were most prominent
in Medpor implants while thickness of the overlying tissue was maximum
in Proplast implants. These findings suggest that complications with
silicone implants may be less than with other porous implants when use
d under burn scarred tissue. (C) 1997 Elsevier Science Ltd for ISBI.