C. Lorenz et al., EARLY WOUND CLOSURE AND EARLY RECONSTRUCTION - EXPERIENCE WITH A DERMAL SUBSTITUTE IN A CHILD WITH 60 PER CENT SURFACE-AREA BURN, Burns, 23(6), 1997, pp. 505-508
A dermal substitute was used for wound management and after early scar
release on a 4-year-old child with mostly full thickness bums coverin
g 60 per cent of the body surface. The biosynthetic material (INTEGRA(
TM) Artificial Skirt) consists of an upper silicone film and a lower l
ayer of porous cross-linked collagen nad chondroitin-6-sulfate as a te
mplate for dermal regeneration. Eight sheets each 4 x 10 in. were used
to cover the patient's whole trunk after staged tangential necrectomy
. In the third and fourth weeks following application the silicone lay
er was easily removed and the newly formed dermis covered with widely
meshed, thin split-thickness autograft. Seven weeks after admission an
early neck contracture was released and the skill defect also coveted
with INTEGRA(TM) Artificial Skin. Following the same principle, trans
plantation of the thin unmeshed autograft was performed successfully 3
weeks later. The good results regarding handling final take, apparent
initial scar reduction, and early recovery may favourably effect init
ial treatment and reconstruction planning after extensive full-thickne
ss burn injuries. (C) 1997 Elsevier Science Ltd for ISBI.