EFFECT OF THE OBSERVANCE OF DIURNAL FAST OF RAMADAN ON DUODENAL-ULCERHEALING WITH LANSOPRAZOLE - RESULTS OF A PROSPECTIVE CONTROLLED-STUDY

Objectives. - The aims of this study were : a) to determine whether pa tients with duodenal ulcer treated with a proton pump inhibitor may fa st during the month of Ramadan, b) to evaluate the result of the treat ment in this condition. Methods. - Fifty-seven patients with acute duo denal ulcer confirmed by endoscopy were included in the study All the patients received 30 mg lansoprazole per day during 4 weeks. After ran domization, patients of group I (n = 27) were dispensed from fasting, while those of group II (n = 30) fasted Endoscopy was performed at the end of the month of the fast. Results. - The course of symptoms was n ot different in groups I and II. There were no ulcer complications. He aling rates at endoscopy were 88.8% and 90% in groups I and II, respec tively Fasting had no influence on the result of duodenal ulcer treatm ent by lansoprazole which was well tolerated Conclusion. - Patients wi th duodenal ulcer treated with lansoprazole may fast without running a ny risk.