ANTIBIOTIC-PROPHYLAXIS IN PATIENTS WITH URINARY RETENTION UNDERGOING TRANSURETHRAL PROSTATECTOMY

Background and Aims: The risk of severe infection and complications in connection with transurethral resection of the prostate (TURP) has cl early increased in patients with urinary retention and an indwelling c atheter. The aim of this study was to determine whether the antibiotic s ciprofloxacin and ceftazidime are equally efficient in preventing in fective complications in these patients.Material and Methods: An open randomized prospective study was carried out on 72 patients with urina ry retention undergoing TURP, to compare of 500 mg of ciprofloxacin (C F) orally twice daily and Ig of ceftazidime (CT) intravenously twice d aily. Results: The incidence of early complications was 26 % in the CF group and 17 % in the CT group. All the complications were minor. On removal of the indwelling catheter, a positive urinary culture was det ected in 6 % of the patients in the CF group and in 3 % in the CT grou p. One month after TURP, a positive urinary culture was detected in 14 % of the patients in the CF group and in 18 % of the CT group. Conclu sions: It is concluded that both of the antibiotics used in this trial were equally effective in the prevention of early urinary and other i nfections and also late complications, in patients with urinary retent ion undergoing TURP.