APPLICATION OF CHEMILUMINESCENCE TO THE S EROLOGICAL DIAGNOSIS OF HUMAN TOXOPLASMOSIS

Diagnostic Products Corporation has chosen chemiluminescent for the ne w kit of quantitative measurement of IgG and qualitative detection of IgM antibodies to Toxoplasma gondii. 878 human sera of principal diagn osis situations were tested, and the results obtained with the IMMULIT E Toxoplasmosis(R). kit were compared with those of the Parasitology a nd Mycology Laboratory of the University of Lille. Chemiluminescent al lows a sensitive and specific determination of immunity. In the same w ay, this method is able to detect earlier specific IgM and IgG during seroconversion. The kit of quantitative measurement of IgG and qualita tive detection of IgM is reproducible and sensitive; this confirms the interest for the pediatric diagnosis of congenital toxoplasmosis.