FISCHER-INDOLIZATION OF 2-SULFONYLOXYPHENYLHYDRAZONES - A NEW AND PRACTICAL APPROACH FOR PREPARING 7-OXYGENATED INDOLES AND APPLICATION TO THE FIRST SYNTHESIS OF EUDISTOMIDIN-A (FISCHER-INDOLIZATION AND ITS RELATED-COMPOUNDS, PART 28)

Authors
MURAKAMI Y WATANABE T TAKAHASHI H YOKOO H NAKAZAWA Y KOSHIMIZU H ADACHI N KURITA M YOSHINO T INAGAKI T OHISHI M WATANABE M TANI M YOKOYAMA Y
Citation
Y. Murakami et al., FISCHER-INDOLIZATION OF 2-SULFONYLOXYPHENYLHYDRAZONES - A NEW AND PRACTICAL APPROACH FOR PREPARING 7-OXYGENATED INDOLES AND APPLICATION TO THE FIRST SYNTHESIS OF EUDISTOMIDIN-A (FISCHER-INDOLIZATION AND ITS RELATED-COMPOUNDS, PART 28), Tetrahedron, 54(1-2), 1998, pp. 45-64
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
1-2
Year of publication
1998
Pages
45 - 64
Database
ISI
SICI code
0040-4020(1998)54:1-2<45:FO2-AN>2.0.ZU;2-D
Abstract
An efficient method for synthesis of 7-oxygenated indoles was establis hed by Fischer indolization of the phenylhydrazones (10) with a sulfon yloxy group at the ortho-position. This method was applied to the firs t synthesis of the calmodulin antagonist eudistomidin-A (2). (C) 1997 Elsevier Science Ltd. All rights reserved.